Anti-DnaJ (E. coli) Antibody, Rabbit, Polyclonal
Artikelnummer:
ASB-OAED00145
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| Artikelname: | Anti-DnaJ (E. coli) Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ASB-OAED00145 |
| Hersteller Artikelnummer: | OAED00145 |
| Alternativnummer: | ASB-OAED00145-50UG |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | IP, WB |
| Spezies Reaktivität: | E. coli |
| Immunogen: | E. coli DnaJ. |
| Alternative Synonym: | b0015,chaperone protein DnaJ,ECK0015,groP,grpC,Heat shock protein J,HSP40. |
| Interacts with DnaK and GrpE to disassemble a protein complex at the origins of replication of phage lambda and several plasmids. Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ, upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK, ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. |
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