TNFRSF10A Antibody

Produktübersicht

• Artikelname: TNFRSF10A Antibody
• Artikelnummer: ASB-OAEE00755
• Hersteller Artikelnummer: OAEE00755
• Alternativnummer: ASB-OAEE00755-0.1MG(C100)
• Hersteller: Aviva
• Wirt: Mouse
• Kategorie: Proteine/Peptide
• Applikation: FC
• Spezies Reaktivität: Human
• Immunogen: Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1.
• Konjugation: APC
• Alternative Synonym: APO2,CD261,cytotoxic TRAIL receptor,death receptor 4,DR4,TNF-related apoptosis-inducing ligand receptor 1,TRAIL receptor 1,TRAILR1,TRAILR-1,TRAIL-R1,tumor necrosis factor receptor superfamily member 10A,tumor necrosis factor receptor superfamily member 10a variant 2,tumor necrosis factor receptor superfamily, member 10a.

Produktbeschreibung

Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 0.1 mg/ml
• Klon-Bezeichnung: [DR-4-02]
• Isotyp: IgG1
• NCBI: 8797
• Puffer: The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
• Formulierung: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide