CD264,DCR2,decoy receptor 2,TNF receptor-related receptor for TRAIL,TNF-related apoptosis-inducing ligand receptor 4,TRAIL receptor 4,TRAIL receptor with a truncated death domain,TRAILR4,TRAIL-R4,TRUNDD,tumor necrosis factor receptor superfamily member 10D,tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain.
Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.