CD62,CD62 antigen-like family member P,CD62P,GMP140,GMP-140,granule membrane protein 140,granule membrane protein 140kDa,granulocyte membrane protein,GRMP,LECAM3,leukocyte-endothelial cell adhesion molecule 3,PADGEM,platelet activation dependent granule-external membrane protein,platelet alpha-granule membrane protein,PSEL,P-selectin,selectin P (granule membrane protein 140kDa, antigen CD62).
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.
The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.