Recombinant protein encompassing a sequence within the center region of human EAPII. The exact sequence is proprietary.
Alternative Synonym:
EAP2, AD022, EAPII, TTRAP, hTDP2, dJ30M3.3
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
