Recombinant protein encompassing a sequence within the center region of human CPSF73. The exact sequence is proprietary.
Alternative Synonym:
CPSF73, CPSF-73
This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3-end pre-mRNA processing.
