Recombinant protein encompassing a sequence within the center region of human Tollip. The exact sequence is proprietary.
Alternative Synonym:
IL-1RAcPIP
This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene.
