CXCR4 Antibody

Produktübersicht

• Artikelname: CXCR4 Antibody
• Artikelnummer: ASB-OAPB00002
• Hersteller Artikelnummer: OAPB00002
• Alternativnummer: ASB-OAPB00002-0.1MG
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: ELISA, FC, ICC, IF, IHC-P, IP, WB
• Spezies Reaktivität: Bovine, Human, Mouse, Porcine, Rat
• Immunogen: Anti-CXCR4 antibody (1009) was raised against a peptide corresponding to 14 amino acids near the amino terminus of human CXCR4 isoform b. The immunogen is located within the first 50 amino acids of CXCR4.
• Konjugation: Unconjugated
• Alternative Synonym: CD184,CD184 antigen,chemokine (C-X-C motif) receptor 4,C-X-C chemokine receptor type 4,D2S201E,FB22,fusin,HM89,HSY3RR,LAP3,LAP-3,LCR1,LESTR,leukocyte-derived seven transmembrane domain receptor,lipopolysaccharide-associated protein 3,LPS-associated protein 3,neuropeptide Y receptor Y3,neuropeptide Y3 receptor,NPY3R,NPYR,NPYRL,NPYY3R,SDF-1 receptor,seven transmembrane helix receptor,seven-transmembrane-segment receptor, spleen,stromal cell-derived factor 1 receptor,WHIM,WHIMS,WHIMS1.

Produktbeschreibung

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: Predicted: 40 kDa Observed: 44 kDa (Post-modification: 2 N-linked glycosylation)
• NCBI: 7852
• Formulierung: Liquid. CXCR4 Antibody is supplied in PBS containing 0.02% sodium azide.