TRAIL antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TRAIL. The immunogen is located within the last 50 amino acids of Trail.
Konjugation:
Unconjugated
Alternative Synonym:
Apo-2 ligand,Apo-2L,APO2L,CD253,chemokine tumor necrosis factor ligand superfamily member 10,TL2,TNF-related apoptosis inducing ligand TRAIL,TNF-related apoptosis-inducing ligand,TNLG6A,TRAIL,tumor necrosis factor (ligand) family, member 10,tumor necrosis factor (ligand) superfamily, member 10,tumor necrosis factor apoptosis-inducing ligand splice variant delta,tumor necrosis factor ligand 6A,tumor necrosis factor ligand superfamily member 10,tumor necrosis factor superfamily member 10.
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:26457518, PubMed:10549288). Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
