DR3 antibody was raised against a 20 amino acid peptide near the carboxy terminus of human DR3. The immunogen is located within the last 50 amino acids of DR3.
Konjugation:
Unconjugated
Alternative Synonym:
APO-3,apoptosis inducing receptor,apoptosis-inducing receptor AIR,apoptosis-mediating receptor DR3,apoptosis-mediating receptor TRAMP,DDR3,death domain receptor 3 soluble form,Death receptor 3,death receptor beta,DR3,GEF720,Guanine nucleotide exchange factor 720,LARD,lymphocyte-associated receptor of death,PH domain-containing family G member 5,Pleckstrin homology domain-containing family G member 5,PLEKHG5,Protein WSL,protein WSL-1,TNFRSF12,TR3,TRAMP,tumor necrosis factor receptor superfamily member 25,tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein),WSL-1,WSL-LR.
Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
