F1A antibody was raised against a 14 amino acid peptide near the carboxy terminus of human F1A. The immunogen is located within the last 50 amino acids of F1A alpha.
Konjugation:
Unconjugated
Alternative Synonym:
F1AA,F1A-ALPHA,FEM1-beta,FEM-1-like death receptor binding protein,fem-1-like death receptor-binding protein alpha,fem-1-like in apoptotic pathway protein alpha,protein fem-1 homolog B.
Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
