Anti-Smac antibody (2411) was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of murine Smac. The immunogen is located within the last 50 amino acids of Smac.
Konjugation:
Unconjugated
Alternative Synonym:
0610041G12Rik,1700006L01Rik,AU040403,diablo homolog, mitochondrial,direct IAP binding protein with low PI,direct IAP-binding protein with low pI,second mitochondria-derived activator of caspase,Sm,Smac.
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases (By similarity).
