Anti-EndoG antibody (3035) was raised against a peptide corresponding to 15 amino acids near the amino terminus of human ENDOG. The immunogen is located within amino acids 40-90 of EndoG.
Konjugation:
Unconjugated
Alternative Synonym:
endo G,endonuclease G, mitochondrial,mitochondrial endonuclease G.
Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity).