DAD1 antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human DAD1. The immunogen is located within the last 50 amino acids of DAD1.
Konjugation:
Unconjugated
Alternative Synonym:
DAD-1,Defender against cell death 1,dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1,oligosaccharyl transferase subunit DAD1,oligosaccharyltransferase 2 homolog,oligosaccharyltransferase subunit 2 (non-catalytic),OST2.
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for the assembly of both SST3A- and SS3B-containing OST complexes. Required for efficient N-glycosylation. Loss of the DAD1 protein triggers apoptosis.
