NADE antibody was raised against a peptide corresponding to 14 amino acids near the middle of human NADE. The immunogen is located within the last 50 amino acids of NADE.
Konjugation:
Unconjugated
Alternative Synonym:
Bex,brain-expressed X-linked protein 3,DXS6984E,HGR74,NADE,nerve growth factor receptor (TNFRSF16) associated protein 1,Nerve growth factor receptor-associated protein 1,NGFRAP1,ovarian granulosa cell 13.0 kDa protein HGR74,p75NTR-associated cell death executor,protein BEX3.
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.