Adiponectin antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human adiponectin. The immunogen is located within the last 50 amino acids of Adiponectin.
Konjugation:
Unconjugated
Alternative Synonym:
30 kDa adipocyte complement-related protein,ACDC,ACRP30,adipocyte complement-related 30 kDa protein,Adipocyte, C1q and collagen domain-containing protein,adiponectin,adipose most abundant gene transcript 1 protein,adipose specific collagen-like factor,ADIPQTL1,ADPN,APM1,APM-1,GBP28,Gelatin-binding protein,gelatin-binding protein 28.
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
