PIST antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human PIST. The immunogen is located within amino acids 360 - 410 of PIST.
Konjugation:
Unconjugated
Alternative Synonym:
CAL,CFTR-associated ligand,dJ94G16.2,dJ94G16.2 PIST,FIG,fused in glioblastoma,golgi-associated PDZ and coiled-coil motif containing protein,Golgi-associated PDZ and coiled-coil motif-containing protein,GOPC1,PDZ protein interacting specifically with TC10,PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10,PIST.
Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
