Anti-TWEAK antibody (3791) was raised against recombinant human TWEAK protein.
Konjugation:
Unconjugated
Alternative Synonym:
APO3 ligand,APO3/DR3 ligand,APO3L,DR3LG,TNF-related WEAK inducer of apoptosis,TNFSF12-TNFSF13 protein,TNLG4A,tumor necrosis factor (ligand) superfamily, member 12,tumor necrosis factor (ligand) superfamily, member 12-member 13,tumor necrosis factor ligand 4A,tumor necrosis factor ligand superfamily member 12,tumor necrosis factor superfamily member 12,TWEAK,TWE-PRIL.
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.