RP105 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human RP105. The immunogen is located within amino acids 590 - 640 of RP105.
May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).
