MD-1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human MD-1. The immunogen is located within the last 50 amino acids of MD-1.
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).