Anti-PD-1 antibody (4065) was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human PD-1. The immunogen is located within amino acids 210-260 of PD-1.
Konjugation:
Unconjugated
Alternative Synonym:
CD279,hPD-1,hPD-l,hSLE1,PD1,PD-1,programmed cell death 1 protein,programmed cell death protein 1,protein PD-1,SLEB2,systemic lupus erythematosus susceptibility 2.
Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Molekulargewicht:
Human PD-1 has 1 isoform (288aa, 32kD). Mouse PD-1 has 1 isoform 288aa, 32kD) and Rat PD-1 also has one isoform (287aa, 32kD). 4065 can detect human, mouse and rat.
