MICA antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human MICA. The immunogen is located within the last 50 amino acids of MICA.
Konjugation:
Unconjugated
Alternative Synonym:
HLA class I antigen,major histocompatibility complex class I chain-related protein A,MHC class I chain-related protein A,MHC class I polypeptide-related sequence A,MHC class I related chain A,MHC class I related sequence A,MIC-A,PERB11.1,stress inducible class I homolog,truncated MHC class I polypeptide-related sequence A,truncated MICA.
Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.