The antiserum was produced against synthesized peptide derived from human RhoA at amino acid range 144-193
Alternative Synonym:
ARHA, ARH12, RHO12, EDFAOB, RHOH12
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
