Synthesized peptide derived from the Internal region of human RhoGEF p115. Location: 140-220aa.
Alternative Synonym:
LSC, GEF1, IMD62, LBCL2, SUB1.5, P115-RHOGEF
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
