Synthesized peptide derived from human RIP2 around the non-phosphorylation site of S176. Location: 120-200aa.
Alternative Synonym:
CCK, RICK, RIP2, CARD3, GIG30, CARDIAK
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
