Synthesized peptide derived from human Rsk-1/2/3/4 around the phosphorylation site of S221/227/S218/232. Location: 160-240aa.
Alternative Synonym:
RSK, HU-1, RSK1, p90Rsk, MAPKAPK1, MAPKAPK1A
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
