Synthesized peptide derived from the Internal region of human SMIF. Location: 80-160aa.
Alternative Synonym:
SMIF, SMAD4IP1, HSA275986, Nbla00360
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants.
