MFN1 ELISA Kit (Human)

Artikelnummer: ASB-OKCD00342
Artikelname: MFN1 ELISA Kit (Human)
Artikelnummer: ASB-OKCD00342
Hersteller Artikelnummer: OKCD00342
Alternativnummer: ASB-OKCD00342-96WELLS
Hersteller: Aviva
Kategorie: Kits/Assays
Applikation: ELISA
Spezies Reaktivität: Human
Alternative Synonym: fzo homolog,hfzo1,hfzo2,mitochondrial transmembrane GTPase Fzo-1,mitochondrial transmembrane GTPase FZO-2,mitofusin-1,putative transmembrane GTPase,transmembrane GTPase MFN1.
Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12475957, PubMed:12759376, PubMed:27920125, PubMed:28114303). Membrane clustering requires GTPase activity (PubMed:27920125). It may involve a major rearrangement of the coiled coil domains (PubMed:27920125, PubMed:28114303). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12475957, PubMed:12759376). Overexpression induces the formation of mitochondrial networks (in vitro) (PubMed:12759376). Has low GTPase activity (PubMed:27920125, PubMed:28114303).
Detektionsbereich: 0.156-10ng/mL
Sensitivitaet: < 0.059 ng/mL
NCBI: 55669
UniProt: Q8IWA4
Proben: Tissue homogenates, cell lysates and other biological fluids