CCN family member 2,connective tissue growth factor,CTGF,HCS24,hypertrophic chondrocyte-specific protein 24,IBP-8,IGF-binding protein 8,IGFBP8,IGFBP-8,insulin-like growth factor-binding protein 8,NOV2.
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
