Ccn,CCN family member 2,cellular communication network factor 1,Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24),Ctgf,fibroblast inducible secreated protein,fibroblast inducible secreted protein,Fis,fisp-12,Fisp12,Hcs2,Hcs24,hypertrophic chondrocyte-specific gene product 24,hypertrophic chondrocyte-specific protein 24,Protein FISP-12.
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity).
