ALPS5,CD,CD152,celiac disease 3,CELIAC3,CTLA-4,cytotoxic T lymphocyte associated antigen 4 short spliced form,cytotoxic T-lymphocyte protein 4,Cytotoxic T-lymphocyte-associated antigen 4,cytotoxic T-lymphocyte-associated serine esterase-4,GRD4,GSE,IDDM12,insulin-dependent diabetes mellitus 12,ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4.
Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.