C358B7.1,P18,RING-type E3 SUMO transferase UBC9,SUMO-1-protein ligase,SUMO-conjugating enzyme UBC9,SUMO-protein ligase,UBC9,ubiquitin carrier protein 9,ubiquitin carrier protein I,ubiquitin conjugating enzyme 9,ubiquitin conjugating enzyme E2I,Ubiquitin-conjugating enzyme E2 I,ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9),ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast),ubiquitin-conjugating enzyme UbcE2A,ubiquitin-like protein SUMO-1 conjugating enzyme,ubiquitin-protein ligase E2I,ubiquitin-protein ligase I.
Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at Lys-386.