epididymis luminal protein 117,epididymis secretory protein Li 53,HEL-117,HEL-S-53,NDGOA,neuron cytoplasmic protein 9.5,PARK5,PGP 9.5,PGP9.5,PGP95,SPG79,ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase),ubiquitin carboxyl-terminal hydrolase isozyme L1,ubiquitin thioesterase L1,ubiquitin thiolesterase,Uch-L1.
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.