UBE2D1 Recombinant Protein (Human), E. coli

Produktübersicht

• Artikelname: UBE2D1 Recombinant Protein (Human), E. coli
• Artikelnummer: ASB-OPED00151
• Hersteller Artikelnummer: OPED00151
• Alternativnummer: ASB-OPED00151-100UG
• Hersteller: Aviva
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Alternative Synonym: (E3-independent) E2 ubiquitin-conjugating enzyme D1,E2 ubiquitin-conjugating enzyme D1,E2(17)KB1,SFT,stimulator of Fe transport,UBC4/5,UBC4/5 homolog,UBCH5,UBCH5A,ubiquitin carrier protein D1,ubiquitin conjugating enzyme E2D 1,ubiquitin-conjugating enzyme E2 D1,ubiquitin-conjugating enzyme E2(17)KB 1,ubiquitin-conjugating enzyme E2-17 kDa 1,ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast),ubiquitin-protein ligase D1.

Produktbeschreibung

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:22496338). In vitro catalyzes Lys-48-linked polyubiquitination (PubMed:20061386). Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1 (PubMed:18042044, PubMed:18359941). Ubiquitinates STUB1-associated HSP90AB1 in vitro (PubMed:18042044). Lacks inherent specificity for any particular lysine residue of ubiquitin (PubMed:18042044). Essential for viral activation of IRF3 (PubMed:19854139). Mediates polyubiquitination of CYP3A4 (PubMed:19103148).

Produkteigenschaften

• Molekulargewicht: 17 kDa
• NCBI: 7321
• Reinheit: >95% (SDS-PAGE)
• Formulierung: Liquid. In 20mM TRIS-HCl, pH 8.0, containing 0.5mM DTT.