The immunogen is a synthetic peptide directed towards the C terminal region of human NR3C2
Alternative Synonym:
MR, MCR, MLR, NR3C2VIT
NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
