IRF8 Antibody - N-terminal region

Artikelnummer: ASB-P100841_P050
Artikelname: IRF8 Antibody - N-terminal region
Artikelnummer: ASB-P100841_P050
Hersteller Artikelnummer: P100841_P050
Alternativnummer: ASB-P100841_P050-25UL,ASB-P100841_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IRF8
Alternative Synonym: ICSBP, IRF-8, ICSBP1, IMD32A, IMD32B, H-ICSBP
Interferon regulatory factor 8 (IRF8, interferon consensus sequence-binding protein, Ion ChannelSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-. and IFN-.. IRF family proteins also control expression of IFN-. and IFN-.-regulated genes that are induced by viral infection.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 48kDa
NCBI: 3394
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunohistochemistry with Human Intestine tissue
Immunohistochemistry with Human Liver cell lysate tissue
WB Suggested Anti-IRF8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Host: Rabbit
Target Name: IRF8
Sample Tissue: Human Ovary Tumor
Antibody Dilution: 1.0ug/ml
25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. An isoform containing the peptide sequence is present at 37 kDa and the protein may also be ubiquitinated.
Host: Rabbit
Target Name: IRF8
Sample Tissue: Human DLD1 Whole Cell
Antibody Dilution: 1ug/ml
Host: Rabbit
Target Name: IRF8
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 3ug/ml
IRF8 antibody - N-terminal region (P100841_P050) in Human Ovary Tumor using Western Blot