Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human MEF2C
Alternative Synonym:
DEL5q14.3, C5DELq14.3
MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. MEF2C may also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
