TFAP2A antibody - C-terminal region (P100878_T100), Rabbit, Polyclonal
Artikelnummer:
ASB-P100878_T100
Hersteller Artikelnummer:
P100878_T100
Alternativnummer:
ASB-P100878_T100-100UL, ASB-P100878_T100-25UL
Hersteller:
Aviva
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Canine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human TFAP2A
Alternative Synonym:
AP-2, BOFS, AP2TF, TFAP2, AP-2alpha
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5-GCCNNNGGC-3 and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM].
