TCEB1 antibody - N-terminal region (P100963_P050), Rabbit, Polyclonal
Artikelnummer:
ASB-P100963_P050
Hersteller Artikelnummer:
P100963_P050
Alternativnummer:
ASB-P100963_P050-100UL, ASB-P100963_P050-25UL
Hersteller:
Aviva
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Canine, Human, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human TCEB1
Alternative Synonym:
SIII, TCEB1
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.
