The immunogen is a synthetic peptide directed towards the C terminal region of human NUCB1
Alternative Synonym:
NUC, CALNUC
Calnuc or NUCB1 belongs to the nucleobindin family. It is a major calcium-binding protein of the Golgi and is a good Golgi marker. It may be involved in calcium homeostasis. Calnuc also plays roles in regulation of levels of .-amyloid precursor protein (APP) and its proteolytic metabolites to further affect the patho/physiological functions of APP including Alzheimers disease pathogenesis. Useful for immunohistochemistry and western blot.
