Human Noggin protein, His tag (Animal-Free)

Produktübersicht

• Artikelname: Human Noggin protein, His tag (Animal-Free)
• Artikelnummer: ASC-PRP1059
• Hersteller Artikelnummer: PRP1059
• Alternativnummer: ASC-PRP1059-5, ASC-PRP1059-20, ASC-PRP1059-100, ASC-PRP1059-1
• Hersteller: Abbkine Scientific
• Kategorie: Proteine/Peptide
• Alternative Synonym: NOG, Noggin, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1, SYNS1A

Produktbeschreibung

Noggin is a 46.2 kDa bioactive protein, which exists as a disulfide-linked homodimer (each chain 23.1 kDa). Noggin binds members of the transforming Growth Factors-beta (TGF beta) superfamily signaling proteins, such as bone morphogenetic protein-4 (BMP-4), which inactivates their activities. As a extracellular antagonist of BMP proteins, Noggin involves in the development of many body tissues, including nerve tissue, muscles, and bones. In addition, Noggin is able to inhibit chondrocyte differentiation through its interaction with GDF5.

Produkteigenschaften

• Molekulargewicht: The protein has a calculated MW of 49.11 kDa. The protein migrates as 27 kDa under reducing condition (SDS-PAGE analysis).
• Tag: Noggin
• UniProt: Q13253
• Reinheit: >98% as determined by SDS-PAGE.
• Formulierung: The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
• Sequenz: Amino acid sequence derived from Human Noggin (Gln28-Cys232) (NP_005441.1) was expressed with 6*His tag at the C-terminus

Anwendungsbeschreibung

• Anwendungsbeschreibung: Human