Human 4-1BBL Protein, His tag (Animal-Free)

Produktübersicht

• Artikelname: Human 4-1BBL Protein, His tag (Animal-Free)
• Artikelnummer: ASC-PRP1217
• Hersteller Artikelnummer: PRP1217
• Alternativnummer: ASC-PRP1217-5, ASC-PRP1217-20, ASC-PRP1217-100, ASC-PRP1217-1
• Hersteller: Abbkine Scientific
• Kategorie: Biochemikalien
• Alternative Synonym: 4-1BB ligand, CD137L, TNLG5A, TNFSF9, Tumor necrosis factor ligand superfamily member 9

Produktbeschreibung

4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFkappaB, c-Jun, and p38 downstream signal pathways activation.Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer.

Produkteigenschaften

• Molekulargewicht: 20.4 kDa
• Tag: 4-1BBL
• NCBI: 8744
• UniProt: P41273
• Reinheit: > 95 % as determined by SDS-PAGE
• Formulierung: Lyophilized from sterile PBS,pH 7.4.
• Sequenz: Amino acid sequence derived from Human 4-1BBL Protein (Arg71-Glu254) (P41273) was expressed with 6*His tag at the C-terminus.
• Formel: 20.4 kDa

Anwendungsbeschreibung

• Anwendungsbeschreibung: Human