The water-soluble ligand THPTA, Tris(3-hydroxypropyltriazolylmethyl)amine, is a very efficient additive for Cu(I)-catalyzed azide-alkyne click reactions (CuAAC) using CuSO4 or baseclicks Cu-Reactor (BCMI-009, incl. also in the Oligo Link Kit BCK-OL). It speeds-up the reactions plus maintaining the Cu(I) oxidation state of the copper source to protect your biomolecules from possible damage and degradation. The ligand is often used for aqueous reactions, including labeling of living cells, labeling of oligonucleotides or labeling of proteins without the need of denaturation of the secondary structures. THPTA is an alternative to the water-insoluble TBTA (Tris((3-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine).
Molekulargewicht:
434.5 g/mol
Reinheit:
98% (HPLC)
Formulierung:
Solid
CAS Nummer:
[760952-88-3]
Formel:
C18H30N10O3
Anwendungsbeschreibung:
click chemistry
THPTA
Tris(3-hydroxypropyltriazolylmethyl)amine
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