A synthesized peptide derived from human FADD Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Alternative Synonym:
FADD, GIG3, MORT1, Protein FADD
Boster Bio Anti-FADD Monoclonal Antibody catalog M00237-1. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Mouse.
