A synthesized peptide derived from human DDX58 Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.
Alternative Synonym:
DDX58, DEAD box protein 58, RIG 1, RIG I, RIG-I
Boster Bio Anti-DDX58 Monoclonal Antibody catalog M00244. Tested in WB, IP applications. This antibody reacts with Human.
