Human recombinant OGG1 (8-oxoguanine DNA glycosylase) protein, AF
Artikelnummer:
BOB-PROTO15527-2-100UG
Hersteller Artikelnummer:
PROTO15527-2-100ug
Alternativnummer:
BOB-PROTO15527-2-100UG-100UG
Hersteller:
Boster Bio
Kategorie:
Proteine/Peptide
Applikation:
Cell Culture
Spezies Reaktivität:
Human
Alternative Synonym:
HMMH, MUTM, OGH1, HOGG1
8-oxoguanine DNA glycosylase-1 (OGG1) is a major DNA glycosylase that plays a critical role in n base-excision repair (BER) of oxidative DNA damage to nuclear and mitochondrial DNA (mtDNA) to remove 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-OH-dG). OGG1 is a 38.8 kDa protein containing 52 amino acid it found in bacterial, archaeal and eukaryotic species. OGG1 in DNA causes G:C to T:A transversions and, therefore, it could be responsible for mutations that lead to carcinogenesis.
Molekulargewicht:
The protein has a calculated MW of 39.61 kDa. The protein migrates as 40 kDa under reducing condition (SDS-PAGE analysis).
The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
