Human recombinant TWEAK (TNF-related weak inducer of apoptosis) protein, AF

Produktübersicht

• Artikelname: Human recombinant TWEAK (TNF-related weak inducer of apoptosis) protein, AF
• Artikelnummer: BOB-PROTO43508-2-100UG
• Hersteller Artikelnummer: PROTO43508-2-100ug
• Alternativnummer: BOB-PROTO43508-2-100UG-100UG
• Hersteller: Boster Bio
• Kategorie: Proteine/Peptide
• Applikation: Cell Culture
• Spezies Reaktivität: Human
• Alternative Synonym: TNFSF12, DR3LG, Apo3 Ligand

Produktbeschreibung

TNF-related weak inducer of apoptosis (TWEAK) is a type II membrane protein of the tumor necrosis factor (TNF) family members, high levels expression in human brain, muscle, heart, spleen, and thymus. TWEAK is a 17.3 kDa protein containing 129 residues. TWEAK induce apoptosis through cognate receptor Fn14 activate caspase-8 and caspase-3, in HSC3 cells KATO-III gastric adenocarcinoma cells and IFN-gamma-treated HT-29. TWEAK stimulate inflammatory cytokines in HT-29, A375 cells, WI-38 fibroblast sand astrocytes.

Produkteigenschaften

• Molekulargewicht: The protein has a calculated MW of 17.88 kDa. The protein migrates as 18 kDa under reducing condition (SDS-PAGE analysis).
• Tag: His Tag (C-term)
• UniProt: O43508
• Quelle: Escherichia coli
• Formulierung: The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0. If you have any concerns or special requirements, please confirm with us.
• Sequenz: MKGRKTRARRAIAAHYEVHPRPGQDGAQAGVDGTVSGWEEARINSSSPLRYNRQIGEFIVTRAGLYYLYCQVHFDEGKAVYLKLDLLVDGVLALRCLEEFSATAASSLGPQLRLCQVSGLLALRPGSSLRIRTLPWAHLKAAPFLTYFGLFQVH with polyhistidine tag at the C-terminus.