Human recombinant GDNF (Glial-derived neurotrophic factor) protein, AF
Artikelnummer:
BOB-PROTP39905-3-5UG
Hersteller Artikelnummer:
PROTP39905-3-5ug
Alternativnummer:
BOB-PROTP39905-3-5UG-5UG
Hersteller:
Boster Bio
Kategorie:
Proteine/Peptide
Applikation:
Cell Culture
Spezies Reaktivität:
Human
Alternative Synonym:
ATF, ATF1, ATF2, HFB1-GDNF, HSCR3
Glial cell line-derived neurotrophic factor (GDNF) is the neurotrophic factor, belonging to the GDNF family of ligands (GFL) and identifying as a therapeutic candidate in Parkinsons disease. GDNF is a 23.7 kDa protein containing 211 residues that plays a critical role in promoting the survival and differentiation of midbrain dopamine neurons. Besides, GDNF is revealed to facilitate the development of peripheral tissues such as kidney, pancreas and lung. Additionally, as a member of GFL, GDNF also takes part in the progression of tumor.
Molekulargewicht:
The protein has a calculated MW of 16.01 kDa. The protein migrates as 16 kDa under reducing condition (SDS-PAGE analysis).
The protein was lyophilized from a 0.2 µm filtered solution containing 20 mM sodium citrate, 0.2 M NaCl, pH 3.5. If you have any concerns or special requirements, please confirm with us.
Sequenz:
MSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI with polyhistidine tag at the C-terminus.
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