Human recombinant IL-36 alpha (Interleukin-36 alpha) protein, AF
Artikelnummer:
BOB-PROTQ9UHA7-2-5UG
Hersteller Artikelnummer:
PROTQ9UHA7-2-5ug
Alternativnummer:
BOB-PROTQ9UHA7-2-5UG-5UG
Hersteller:
Boster Bio
Kategorie:
Proteine/Peptide
Applikation:
Cell Culture
Spezies Reaktivität:
Human
Alternative Synonym:
IL36A, Interleukin-1 family member 6 (IL-1F6), FIL1epsilon (FIL1E), Interleukin-1epsilon (IL1E)
Interleukin-36 alpha (IL-36alpha) is an 18 kDa cytokine with 154 amino acid residues. IL-36alpha is one of the IL-36 agonists secreted from keratinocytes. When IL-36alpha binds to the IL-36 receptor, it activates NF-kappaB and MAPK signaling pathways that induce inflammatory responses. In addition, it also stimulates the production of inflammatory cytokines, such as IFN-gamma, TNF-alpha, and IL-6.
Molekulargewicht:
The protein has a calculated MW of 18.05 kDa. The protein migrates as 17 kDa under reducing condition (SDS-PAGE analysis).
The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
Sequenz:
MKIDTPQQGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF with polyhistidine tag at the C-terminus.
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