The TCF/LEF Luciferase Reporter cell line is a stably transfected HEK293 cell line which expresses Renilla luciferase reporter gene under the control of the TCF/LEF response element. This cell line is designed to monitor the transcriptional activity of TCF/LEF and can be used for studying Wnt signaling pathways as well as screening of activators or inhibitors that affect the TCF/LEF transcriptional activity.
Puffer:
Each vial contains 2 ~ 3 x 10 6 cells in 1 ml of 90% FBS + 10% DMSO.
Application Verdünnung:
<h2>Application:</h2>Monitor the TCF/LEF induction activity.Screen for activators or inhibitors of the TCF/LEF signaling pathway. <h2>Culture conditions:</h2>Cells should be grown at 37C with 5% CO2 using DMEM medium supplemented w
Fig-1: Induction of TCF/LEF activity by LiCl in TCF/LEF HEK293 cells.
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